AdultPneumonia, UTI, gynaecological infections, skin & skin structure infections 500 mg IV every 8 hr. Nosocomial pneumonia, peritonitis, presumed infections in febrile neutropenic patient, septicaemia 1 g every 8 hr. Meningitis 2 g every 8 hr. Childn >50 kg Adult dose, >3 mth up to 12 yr 10-20 mg/kg IV every 8 hr. Meningitis 40 mg/kg IV every 8 hr. Febrile episodes in neutropenic patient 20 mg/kg every 8 hr. Renal insufficiency CrCl 26-50 mL/min Recommended dose every 12 hr, 10-25 mL/min ½ recommended dose every 12 hr, <10 mL/min ½ recommended dose every 24 hr.
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